n this candid and darkly funny conversation, Rick Rosner and Scott Douglas Jacobsen navigate topics few would dare mix—bodily quirks, gut biology, aging, and self-improvement. Rosner begins by unpacking his compulsive skin-picking habit and the medical realities of hemorrhoid surgery and anal fissures with clinical precision and self-deprecating humor. The discussion then shifts to the biology of feces, the evolutionary disgust response, and a dog’s poop-eating habits linked to Cushing’s disease. From there, Rosner reflects on moviegoing, Kevin Smith’s unlikely romance, and the virtues of artificial sweeteners. The talk ends with longevity science—fisetin, curcumin, and rapamycin—offered as modern elixirs for an aging body and restless mind.








